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Dr. Emmanuel Edet Effa

Senior Lecturer
Internal Medicine
eeeffa@unical.edu.ng

Dr. Emmanuel Effa is a Senior Lecturer in Medicine at the University of Calabar, honorary chief Consultant physician/Nephrologist to the University of Calabar Teaching Hospital, as well as the acting head of Internal Medicine at both institutions since October 2016.He obtained his MBBCh degree in 1999 from the University of Calabar and trained in Nephrology at the University College Hospital, Ibadan, South west Nigeria. He was awarded the Fellowship of Medical College of Physique (FMCP) by the National Postgraduate Medical College of Nigeria in 2010 and won the Dr. Mabayoje prize for the best candidate in Nephrology for that year. He is an International Society of Nephrology (ISN) scholar following a 6-month clinical nephrology fellowship at Division of Nephrology and Hypertension at the Department of Medicine, University of cape Town/Groote Schuur Hospital, Cape Town, South Africa. He completed a postgraduate certificate in medical education with the Centre for Medical Education of the University of Dundee, Scotland. Dr. Effa pioneered kidney care services at the University of Calabar Teaching Hospital in 2009 and supervised the establishment of its haemodialysis unit. Presently, he also serves as a Cross River State Government appointed Consultant Nephrologist to the MTN Foundation Haemodialysis project at the General Hospital, Calabar. He teaches medical students, supervises house officers, trains and mentors resident doctors and supervises nurses and other allied health staff in his team. He has served as external examiner to the MBBCh programme of College of Health sciences, Abia State University. His research interests include general medicine, acute kidney injury and renal replacement therapy. He also has experience insystematic reviews,priority setting and clinical audits. He has authored and co-authored several reviews published in the ‘Cochrane Library’, a high impact journal of the Cochrane Collaboration. He serves as editor with the Cochrane Infectious Diseases and Cochrane Kidney and Transplant groups as well as the Editor-in-chief of the Cross River Journal of Medicine, a peer reviewed biomedical journal published by the Nigerian Medical Association, Cross River State chapter. He is a peer referee for several journals including Medicine, Nephrology, BMC Health Services, Nigerian journal of Medicine, Tropical Journal of Nephrology, Journal of Clinical Epidemiology and Journal of Medicine in Africa. He has over 35 published scholarly articles in both local and international journals. Dr. Effa coordinates training in Evidence Based Healthcare and systematic reviews at Cochrane Nigeria located at the Calabar Institute of Tropical Diseases Research and Prevention, UCTH in collaboration with the Effective Healthcare Research Consortium at the Liverpool School of Tropical Medicine and the Cochrane Africa Network. He serves as the co-principal investigator for this project. He is also the Principal Investigator for an ISN funded “Early Kidney evaluation and prevention study” presently ongoing in Cross River State. He is the Co-Principal Investigator for the West African Hub of the Cochrane African Network, a project focused on systematic review priority setting, evidence dissemination and stakeholder engagement across West, East and Southern Africa. He has attended several nephrology conferences organised by the American Society of Nephrology, International Society of Nephrology, European Renal Association, South African Renal Association as well as the Nigerian Association of Nephrologists(NAN). He was the LOC chairman for the 27th Annual conference of NAN in Calabar in 2015. He served as Examination Officer in the department of Internal medicine between 2014 and 2016 as well as a member of the Faculty Lecture Committee of the Faculty of Medicine, University of Calabar from 2014 till date.

Effa EE, Bukirwa HM. Azithromycin for treating uncomplicated typhoid and paratyphoid fever (enteric fever). Cochrane Database of Systematic Reviews 2008, Issue 4. Art. No.: CD006083. DOI: 10.1002/14651858.CD006083.pub2


Esu E, Effa EE, Opie ON, Uwaoma A, Meremikwu MM. Artemether for severe malaria. Cochrane Database of Systematic Reviews 2014, Issue 9. Art. No.: CD010678. DOI: 10.1002/14651858.CD010678.pub2.


Effa EE, Lassi ZS, Critchley JA, Garner P, Sinclair D, Olliaro PL, Bhutta ZA. Fluoroquinolones for treating typhoid and paratyphoid fever (enteric fever). Cochrane Database Syst Rev. 2011 Oct 5;(10):CD004530. Review.


Okonkwo RI, Weidmann AE, Effa EE. Renal and Bone Adverse Effects of a Tenofovir-Based Regimen in the Treatment of HIV-Infected Children: A Systematic Review. Drug Saf. 2015 Dec 21.


Effa EE, Okpa HO, Mbu PN, Epoke EJ, Otokpa ED. Acute Kidney Injury in Hospitalized patients at the University of Calabar Teaching Hospital: An aetiological and outcome study. IOSR Journal of Dental and Medical Sciences. Volume 14, Issue 3 Ver. VII (Mar. 2015),55-9


Ekrikpo UE, Udo AI, Ikpeme EE, Effa EE. Haemodialysis in an emerging centre in a developing country: a two-year review and predictors of mortality. BMC Nephrol. 2011 Oct 2;12:50.


Udomah FP, Ekrikpo UE, Effa EE, Salako B, Arije A, Kadiri S. Association between Urinary N-Acetyl-Beta-D-Glucosaminidase and Microalbuminuria in Diabetic Black Africans. International Journal of Nephrology, vol. 2012, Article ID 235234, 5 pages, 2012. doi:10.1155/2012/235234


Ekrikpo UE, Effa EE, Akpan EE. Ectopic thoracic kidney and end-stage renal disease in a 38-year-old nigerian. Case Rep Nephrol. 2013;2013:158494. doi: 10.1155/2013/158494. Epub 2013 May 2


Akpan EE, Ekrikpo UE, Effa EE, Udo AA, Kadiri S. Assessment of dyslipidemia in pre-dialysis patients in south-west Nigeria. Niger Med J 2014;55:214-9


Meremikwu M, Udoh E, Nwagbara B, Effa E, Oringanje C, Edet B et al. Prority setting for Systematic Review of healthcare interventions in Nigeria. Health Policy 99 (2011) 244–24


Meremikwu MM, Odey F, Oringanje C, Oyo-Ita A, Effa E, Esu EB, Eyam E, Oduwole O, Asiegbu V, Alaribe A, Ezedinachi EN. Open-label trial of three dosage regimens of fixed-dose combination of artemisinin and naphthoquine for treating uncomplicated falciparum malaria in Calabar, Nigeria. Malar J. 2012 Dec 11;11:413. doi: 10.1186/1475-2875-11-413.


Udoh E, Oyo-Ita A, Odey F, Effa E, Esu E, Oduwole O, Chibuzor M, Meremikwu M. Management of uncomplicated malaria in underfives in private and public health facilities in South-eastern Nigeria: a clinical audit of current practices. Malar Res Treat. 2013;2013:575080. doi: 10.1155/2013/575080. Epub 2013 Jan 21.


Odey F, Esu E, Effa E, Udoh E, Oduwole O, Chibuzor M, Oyo-Ita A, Meremikwu M. Management of severe malaria in children under 5 years of age in private and public health facilities in Cross River State, southeastern Nigeria: an audit of current practices. Clinical Audit 2013:5 43–48


Esu E, Effa E, Udoh E, Oduwole O, Odey F, Chibuzor M, Oyo-Ita A, Meremikwu M. Utilization of intermittent preventive treatment for malaria among pregnant women attending antenatal clinics in health facilities of Cross River State, Nigeria. Research and Reports in Tropical Medicine 2013:4 29–35


Umoh VA, Out A, Okpa H, Effa E. The Pattern of Respiratory Disease Morbidity and Mortality in a Tertiary Hospital in Southern-Eastern Nigeria. Pulm. Med. 2013;2013:581973. doi: 10.1155/2013/581973. Epub 2013 Dec 17.


Bello S, Effa EE, Oku OE, Olabisi O. Handwashing practice among healthcare providers in a teaching hospital in southern Nigeria. Int J Infect Control 2013, v9:i4 doi: 10.3396/IJIC.v9i4.031.13


Okpa HO, Enang OE, Effa EE, Essien OE, Mbu PN. Comparative Analysis of Atherogenic Index of plasma and its relationship with cardiovascular risk among patients with Diabetes Mellitus and concurrent Diabetes Mellitus with Hypertension attending Endocrinology Clinic In A Tertiary Hospital South- South Nigeria. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)e-ISSN: 2279-0853, p-ISSN: 2279-0861.Volume 14, Issue 8 Ver. VIII (Aug. 2015), PP 102-107.


Meremikwu M, Udoh E, Esu E, Chibuzor M, Effa E, Oduwole O, Arikpo D, Odey F. Facility-Based treatment of underfive diarrhoea in Cross River State: A clinical audit. Niger J Paed 2015; 42 (4): 314 - 318


Okusanya BO, Oduwole O, Effa EE. Immediate postabortal insertion of intrauterine devices. Cochrane Database Syst Rev. 2014 Jul 28;7:CD001777.


Udoh A, Effa EE, Oduwole O, Okusanya BO, Okafo O. Antibiotics for treating septic abortion. Cochrane Database of Systematic Reviews 2016, Issue 7. Art. No.: CD011528. DOI: 10.1002/14651858.CD011528.pub2.


Awobusuyi JO, Bakare O, Dada A, Adamu U, Abasi- Ekong Udobang, Effa E, Ummate I, Uwakwem A et al. Indices of Kidney Damage in Nigeria: A Survey of 8077 Subjects in the Six Geopolitical Zones of the Country. Tropical Journal of Nephrology Vol.10 No 2, December, 2015 95 – 105.


Udoh E, Odey F, Effa E, Meremikwu M. Facility-Based evaluation of under-five children with diarrhea in Cross River State, Nigeria: A clinical audit. Int J Contemp Pediatr. 2016 Nov;3(4):1173-1177


Effa EE, Esu EB, Meremikwu MM. Evidence based medicine: Basic principles of practice. Journal of Medicine in Africa 2016 1(1):11-13


Effa E, Webster A. Pharmacological interventions for the management of acute hyperkalaemia in adults. Nephrology. 2017.  22: 5–6. doi: 10.1111/nep.12895.


Wearne N, Kilonzo K, Effa E, Davidson B, Nourse P, Ekrikpo U, Okpechi I. Continuous ambulatory peritoneal dialysis: perspectives on patient selection in low- to middle-income countries. International Journal of Nephrology and Renovascular Disease. 2017;10:1-9. doi:10.2147/IJNRD.S104208.


Ekrikpo UE, Effa EE, Akpan EE, Obot AS, Kadiri S. Clinical Utility of urinary β2 microglobulin in detection of early nephropathy in African Diabetes Mellitus Patients International Journal of Nephrology, Volume 2017, Article ID 4093171, 8 pages


Effa E, Ojo O, Ihesie A, Meremikwu, MM. Deinfibulation for treating urologic complications of type III female genital mutilation: A systematic review. Int J Gynecol Obstet, 2017, 136: 30–33. doi:10.1002/ijgo.12045


Effa EE, Ekrikpo UE, Borkum M, Rayner BL, Heering P, Okpechi IG. Clinical profile and outcome of patients with biopsy-proven acute interstitial nephritis in Cape Town: a 10-year review. Clin Nephrol. 2017 Apr 25. doi: 10.5414/CN109163


Ikpeme A, Ani N, Ago B, Effa E, Kosoko-Lasaki O, Ekpenyong A. The Value of Mobile Untrasound Services in Rural Communities in South-South Nigeria. Open Access Maced J Med Sci.2017 Dec 15; 5(7):1011-1015.https://doi.org/10.3889/oamjms.2017.191


Udoh UA, Ochang EA, Effa EE, Onyedibe KI, Usang UE, Osakwe OE: Evaluation of tigecycline activity on wound isolates of methicillin-resistant Staphylococcus aureus from hospital and community-acquired infections in Cross River State, Nigeria. Cross River J Med 2017, 1(1); 18-25


Otu A, Akpan M, Effa E, Umoh V, Enang O. Prevalence of type 2 diabetes mellitus in Southern Cross River: a cross-sectional observational survey. Int J Diabetes Dev Ctries. https://doi.org/10.1007/s13410-018-0606-5


Ekrikpo UE, Kengne AP, Bello AK, Effa EE, Noubiap JJ, Salako BL, et al. (2018) Chronic kidney disease in the global adult HIV-infected population: A systematic review and meta-analysis. PLoS ONE 13(4): e0195443. https://doi.org/10.1371/journal. pone.0195443


Ekrikpo UE, Kengne AP, Akpan EE, Effa EE, Bello AK, Ekott JU, George C, Salako BL, Okpechi IG. Medicine (Baltimore). 2018 Apr;97(16):e0380. doi: 10.1097/MD.0000000000010380


Effa EE, Okpa HO, Arije A, Salako BL, Kadiri S. A non-functioning left kidney from renal tuberculosis and a review of literature. Nigerian Journal of Medicine. 2017. 26(4); 375-8


Omowunmi BQ, Awobusuyi JO, Dada A, Udobang A, Effa E. Metabolic syndrome in Nigeria: a survey of six geopolitical zones. LASU Journal of Medical Sciences. 2017. 2(1): 35-9


Mbuagbaw L, Ongolo Zogo P, Kredo T, Durao S, Young T, Effa E, Meremikwu M, Hohlfeld A, Wiysonge C. Cochrane Africa: a network of evidence-informed health-care decision making across sub-saharan Africa. The Pan African Medical Journal. 2018;29:196. doi:10.11604/pamj.2018.29.196.14521

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