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Prof. Daniel Udofia Owu

Professor
Physiology
danielowu@unical.edu.ng

I am a professor in the department of physiology with special interest in Cardiovascular physiology, smooth muscle physiology and gastrointestinal tract physiology

Osim, E. E., Owu, D. U. and Etta, K. M. (1996). Arterial pressure and lipid profile in rats following chronic ingestion of palm oil diets. African Journal of Medicine and Medical Sciences. 25: 335-340.


Owu, D. U., Osim, E. E. and Orie, N. N. (1997). Altered responses of isolated aortic smooth muscle following chronic ingestion of palm oil diets in rats. African Journal of Medicine and Medical Sciences. 26: 83-86.


Owu, D. U., Osim, E. E. and Ebong, P. E. (1998). Serum liver enzymes profile of Wistar rats following chronic consumption of fresh or oxidized palm oil diets. Acta Tropica. 69: 65-73.


Eno, A. E., Itam, E. H., Owu, D. U., Ettarh, R. R. and Konya, R. S. (1999). Haemolytic activity of the crude extract from Eleophorbia drupifera leaves. Bioscience Research Communications. 11 (2): 89-97.


Ebong, P. E., Owu, D. U. and Isong, E. U. (1999). Influence of palm oil (Elaesis guineensis) on health. Plant Foods for Human Nutrition. 53: 209-222.


Eno, A. E., Owo, O. I., Itam, E. H., Ettarh, R. R., Mfem, C. C. and Owu, D. U. (1999). Contraction of the isolated Guinea pig ileum induced by the crude extract from Eleophorbia drupifera leaves. Global Journal of Pure and Applied Sciences.5: 45-51.


1. Osim, E. E., Owu, D., Isong, E. U. and Umoh, I. B. (1992). Influence of chronic consumption of thermoxidized palm oil diet on platelet aggregation in the rat. Discovery and Innovation. 4: 83-87.


2. Osim, E. E., Owu, D. U, Isong, E. U. and Umoh, I. B. (1994). Influence of chronic consumption of thermoxidized and fresh palm oil diets on basal metabolic rate, body weight and morphology of tissues in rats. Discovery and Innovation. 6: 389-396.


Eteng, M. U., Ettarh, R. R. and Owu, D. U. (2003). Effect of theobromine exposure on haematological parameters in rats. Nigerian Journal of Physiological Sciences.18: 4-8


Owu, D. U., Udoete, U. B., Azah, N. and Eyong, E. U. (2005). Effect of Bonny light crude oil on some haematological parameters of Guinea pigs. Biokemistri. 17(2): 165-170.


Okwari, O. O., Antai, A. B., Owu, D. U., Peters, E. J. and Osim, E. E. (2005). Lung function status of workers exposed to wood dust in timber markets in Calabar, Nigeria. African Journal of Medicine and Medical Sciences. 34: 141-145.


Eteng, M. U., Ibekwe, H. A., Amatey, T. E., Bassey, B. J., Uboh, F. U. and Owu, D. U. (2006). Effect of vitamin C on serum lipids and electrolyte profiles of Albino Wistar rats. Nigerian Journal of Physiological Sciences. 21: 15-19.


Owu, D. U., Antai, A. B., Udofia, K. H., Obembe, A. O., Obasi, K. O. and Eteng, M. U. (2006). Vitamin C improves basal metabolic rate and lipid profile in alloxan-induced diabetes mellitus in rats. Journal of Bioscience. 31: 575-579.


Owu, D. U., Ben, E. E., Antai, A. B., Ekpe, E. A. and Udia, P. M. (2008). Stimulation of gastric acid secretion and intestinal motility by Vernonia amygdalina extract. Fitoterapia. 79: 97-100.


Antai, A. B., Owu, D. U. and Ofem, O. E. (2008). Effect of Rothmannia hispida on gastric acid secretion and cytoprotection in rats. Mary Slessor Journal of Medicine. 8: 32-36


Obembe, A. O., Okwari, O. O., Owu, D. U., Antai, A. B. and Osim, E. E. (2008). Intestinal motility and transit following chronic ingestion of different forms of palm oil diets. Nigerian Journal of Physiological Sciences. 23 (1-2): 95-99


Udia, P. M., Braide, V. B. and Owu, D. U. (2009). Antispasmodic and spasmolytic effects of methanolic extract from seeds of Garcinia kola on isolated rat small intestine. Nigerian Journal of Physiological Sciences. 24 (2): 111-116


Obembe, A. O., Antai, A. B., Owu, D. U., Okwari, O. O., Eteng, M. U. and Osim, E. E. (2010). Bile secretion and palm oil diets in Wistar rats. Nutrition and Food Sciences. 40 (4): 388-394


Obembe, A. O., Owu, D. U., Okwari, O. O., Antai, A. B., Osim, E. E. (2011). Intestinal fluid and glucose transport in Wistar rats following chronic consumption of fresh or oxidised palm oil diet. ISRN Gastroenterology. Volume 2011, Article ID 972838, 5 pages, doi:10.5402/2011/972838


Nwokocha, C. R., Owu, D. U., Ufearo, C. S., Iwuala, M. O. (2011). Comparative study on the efficacy of Garcinia kola in reducing some hepatic heavy metal accumulation in liver of Wistar rats. Journal of Ethnopharmacology. 135: 488-491.


Nwokocha, C. R., Ajayi, I. O., Owu, D. U., Ebeigbe, A. B. (2011). Specificity of vascular reactivity and altered response in experimental malaria. West Indian Medical Journal. 60 (3): 330-335


Nwokocha, CR, Ozuola, RI, Owu, DU, Nwokocha MI, Ugwu AC, (2011). Antihypertensive properties of Allium sativum (garlic) on normotensive and two kidney one clip hypertensive rats. Nigerian Journal of Physiological Sciences. 26 (2): 213-218.


Nwokocha C. R., Nwokocha M. I., Owu, D. U., Edidjana, E., Nwogbo, N., Ekpo, U. and Ufearo, C. S. (2011). Estimation of absorbed cadmium in tissues of male and female albino rats through different routes of administration. Nigerian Journal of Physiological Sciences. 26: 97-101.


Nwokocha, CR, Owu, DU, Nwokocha, MI, Ufearo CS, Iwuala MOE. (2012). Comparative study on the efficacy of Allium sativum (garlic) in reducing some heavy metal accumulation in liver of Wistar rats. Food and Chemical Toxicology. 50: 222-226. doi:10.1016/j.fct.2011.11.003


Nwokocha CR, Nwokocha MI, Owu DU, Obi J, Olatunde B, Ebe C, Nwangwu O, Iwuala MO. (2012). Comparative analysis on the effect of palm oil (Elaeis guineensis) in reducing cadmium and lead accumulation in liver of Wistar rats. Pharmacognosy Research. 4(4):214-8. doi: 10.4103/0974-8490.102266


Nwokocha CR, Nwokocha MI, Owu DU, Ajayi IO, Ebeigbe AB. (2012). Experimental malaria: the in vitro and in vivo blood pressure paradox. Cardiovascular Journal of Africa. 23(2): 98-102. doi: 10.5830/CVJA-2011-059


27. Nwokocha CR, Owu DU, Nwokocha MI, Ufearo CS, Iwuala MO. (2012). Comarative study on the hepatoprotection to heavy metals by Zingiber officinale. Pharmacognosy Research. 4(4):208-13. doi: 10.4103/0974-8490.102263


Nwokocha CR, Nwokocha MI, Aneto I, Obi J, Udekweleze DC, Olatunde B, Owu DU, Iwuala MO. (2012). Comparative analysis on the effect of Lycopersicon esculentum (tomato) in reducing cadmium, mercury and lead accumulation in liver. Food and Chemical Toxicology. 50 (6): 2070-2073


Nwokocha CR, Ufearo, CS, Owu, DU, Idemudo NC, Ojukwu LC. (2012). In vivo distribution of lead in male and female rats after intraperitoneal and oral administration. Toxicology and Industrial Health 28 (2): 131-135. doi: 10.1177/0748233711407955


Owu DU, Obembe AO, Nwokocha CR, Edoho IE, Osim EE. (2012). Gastric ulceration in diabetes mellitus: protective role of vitamin C. ISRN Gastroenterology. Volume 2012, Article ID 362805, 7 pages, doi:10.5402/2012/362805


Owu DU, Nwokocha CR, Obembe AO, Essien AD, Ikpi DE, Osim EE. (2012). Effect of Gongronema latifolium ethanol leaf extract on gastric acid secretion and cytoprotection in streptozotocin-induced diabetic rats. West Indian Medical Journal. 61 (9): 853-860. DOI:10.7727/wimj.2011.040


Nwokocha CR, Owu, DU, Mclaren M, Murray J, Delgoda R, Thaxter K, McCalla G, and Young L. (2012). Possible mechanisms of action of the aqueous extract of Artocarpus altilis (breadfruit) leaves in producing hypotension in normotensive Sprague–Dawley rats. Pharmaceutical Biology, 50(9):1096-102. doi: 10.3109/13880209.2012.658113


Nwokocha CR, Owu DU, Kinlocke K, Murray J, Delgoda R, Thaxter K, McCalla G and Young L. (2012). Possible mechanism of action of the hypotensive effect of Peperomia pellucida and interactions between human cytochrome P450 enzymes. Medicinal and Aromatic Plants 1:105. doi:10.4172/2167-0412.1000105


Nwokocha CR, Owu DU, Gordon A, Thaxter K, McCalla G, Ozolua RI, Young L. (2012). Possible mechanisms of action of the hypotensive effect of Annona muricata (soursop) in normotensive Sprague-Dawley rats. Pharmaceutical Biology. 50(11):1436-41 doi: 10.3109/13880209.2012.684690.


Owu DU, Orie NN, Nwokocha CR, Clapp LH and Osim EE (2013). Comparative effect of type 1 and type 2 diabetes mellitus on vascular responses of rat thoracic aorta to potassium ion channel openers. British Journal of Medicine and Medical Research 3(3): 748-759.


Owu DU, Orie NN, Nwokocha CR, Muzyumba M,Clapp LH, Osim EE (2013). Attenuated vascular responsiveness to K channel openers in diabetes mellitus: The differential role of reactive oxygen species. General Physiology and Biophysics 32, 527–534. doi: 10.4149/gpb_2013057.


Okon, UA, Obembe, AO, Olubobokun TH and Owu, DU. (2013). Anti-gastric ulcerative activity of Ocimum gratissimum in streptozotocin-induced diabetic rats. Journal of Scientific Research and Reports. 2(1): 408-422


Nwokocha C. R., Younger-Coleman, N., Nwokocha, M., Owu, D. U., Asemota, H., Iwuala, M., and Lay-Ekuakille,A. (2013). Analysis of time of measurement and modes of administration of some medicinal plants additives on mercury accumulation in the liver. International Journal of Measurement Technologies and Instrumentation Engineering, 3(3): 60-70.


Nwokocha CR, Younger-Coleman N, Nwokocha M, Owu DU, Iwuala M. (2014). Investigation of effects of time of measurement and modes of administration on cadmium accumulation in rat liver under some medicinal plants food supplemented diet. Pharmacognosy Research. 6(3):240-5. doi: 10.4103/0974-8490.132604.


Nwokocha, CR., Younger-Coleman, N, Nwokocha, M., Owu, D, Iwuala, M. (2014). A comparative study of the effect of some nutritional medicinal plants effect on lead accumulation in the liver following different modes of administration. Pharmacognosy Research. 6: 306-311. DOI: 10.4103/0974-8490.138278


Udia, P. M., Owu, D. U., Ogbonna, O. J. and Takem, L. P. (2015). Possible mechanism of antispasmodic action of Garcinia kola seed extract on isolated Guinea pig ileum. British Journal of Medicine and Medical Research. 6(7): 688-698


Ani, E. J., Ofem, O. E., Owu, D. U., Osim, E. E. (2015). Distortions in sensitivity of carotid baroreceptor reflexes in rabbits following consumption of two forms of palm oil diets. British Journal of Medicine and Medical Research 8(3): 245-255


Ani, E. J., Nna, V. U., Owu, D. U., Osim, E. E. (2015). Effect of chronic consumption of two forms of palm oil diet on serum electrolytes, creatinine and urea in rabbits. Journal of Applied Pharmaceutical Science 5 (06): 115-119


Oka, V. O., Udefa, A. L, Nna, V.U. and Owu, D. U. (2015). Sildenafil citrate and tramadol administered separately and in combination affects basal metabolic rate, triiodothyronine (T3) and cortisol levels in albino Wistar rats. Trends in Medical Research 10 (3): 51-62


Udia, P. M., Takem, L. P., Ufot, U. F., Antai, A. B., Owu, D. U. (2016). Insulin and alpha amylase levels in alloxan-induced diabetic rats and the effect of Rothmannia hispida (K. Schum) Fagerl leaf extract. The Journal of Phytopharmacology; 5(1):1-5


Nkanu, E. E., Owu, D. U. and Osim, E. E. (2017): Altered potassium ion channel function as a possible mechanism of increased blood pressure in rats fed thermally oxidized palm oil diets, Journal of Dietary Supplements, DOI: 10.1080/19390211.2017.1350248


Owu, D. U., Nwokocha, C. R., Ikpi, D. E. and Ogar, E. I. (2016). Effect of vitamin C supplementation on platelet aggregation and serum electrolytes levels in streptozotocin-induced diabetes mellitus in rats. Niger. J. Physiol. Sci. 31: 055-061.


Nna, V. U., Usman, U. Z., Ofutet, E. O. and Owu, D. U. (2017). Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride-induced oxidative stress in the uterus and ovaries of female Wistar rats. Food and Chemical Toxicology. 102: 143-155.

No Results for Research Works done
No Results for Conferences Attended
No Results for Grants/Awards Received